Product Information
- Fluoro-N,N,N',N'-bis(tetramethylene)formamidinium hexafluorophosphateFluoro-dipyrrolidinocarbenium hexafluorophosphateBis(tetramet hylene)fluoroformamidinium hexafluorophosphate
- BTFFH~Fluorobis(tetramethylene)formamidinium hexafluorophosphate
- Fluoro-N,N,N,N-bis(tetramethylene)formamidinium hexafluorophosphate
- 1-[Fluoro(Pyrrolidin-1-Yl)Methylidene]Pyrrolidinium Hexafluorophosphate
- Btffh
BTFFH is a fluorouronium coupling reagent used for amide formation and peptide synthesis. BTFFH is effective in presence of sterically hindered carboxylic acids and hindered or electron deficient amines, achieving high yields in liquid and solid phase. BTFFH activates the carboxylic acid by forming the acyl fluoride, which are reported to be less susceptible to racemisation than acyl chlorides. Despite similar performances that are observed with the fluoroformamidinium salts BTFFH and TFFH, the first reagent is generally preferred since TFFH generates toxic by-products
Chemical properties
Technical inquiry about: 3D-FB15685 BTFFH
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