BAPTA

CAS: 85233-19-8

Ref. 3D-FB16297

Product Information

• Name: BAPTA
• Synonyms: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid2,2'-(Ethylenedioxy)dianiline-N,N,N',N'-tetraacetic acid, 1,2-Bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid, 2,2',2'',2'''-[Ethane-1,2-Diylbis(Oxybenzene-2,1-Diylnitrilo)]Tetraacetate, 2,2',2'',2'''-[Ethane-1,2-Diylbis(Oxybenzene-2,1-Diylnitrilo)]Tetraacetic Acid, 2-[2-[2-[2-[Bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid, Bapta, Glycine, N,N′-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-, N,N′-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine]

Description

BAPTA is a fluorescent probe that binds to cytosolic calcium and can be used to measure intracellular calcium levels. It can also be used as a fluorescence probe for the measurement of mitochondrial membrane potential. BAPTA is a potent inhibitor of neuronal death induced by excess cytosolic calcium, which leads to activation of calcium-dependent proteases and cell lysis. The mechanism by which BAPTA inhibits neuronal death is unclear, but it may be due to its ability to modulate mitochondrial membrane potential or regulate Ca2+ release from intracellular stores. BAPTA has been shown to inhibit the polymerase chain reaction (PCR) in cells and tissues and can also inhibit the transcriptional activity of nuclear DNA. In addition, BAPTA can inhibit the function of ryanodine receptors in cells, leading to an increase in cytosolic Ca2+.

• Brand: Biosynth

Chemical properties

• Molecular weight: 476.43 g/mol
• Formula: C₂₂H₂₄N₂O₁₀
• Purity: Min. 97 Area-%
• Color/Form: White Powder