N1,N2-Bis(2,4,6-trimethoxyphenyl)ethanediamide

CAS: 957476-07-2

Ref. 3D-FB171929

Product Information

• Name: N1,N2-Bis(2,4,6-trimethoxyphenyl)ethanediamide
• Synonyms: N,N'-Bis(2,4,6-trimethoxyphenyl)oxalamideBTMPO
• Brand: Biosynth

Description

Adriamycin is a cytotoxic drug that inhibits the growth of cells by causing cross-linking in DNA. It is an analogue of the naturally occurring molecule bis(2,4,6-trimethoxyphenyl)ethanediamide. Adriamycin has been shown to inhibit cell proliferation in vitro and in vivo by interfering with DNA synthesis. This agent also inhibits the production of proteins and lipids needed for cellular division by binding to the purine base adenine. Adriamycin binds to the enzyme ribonucleotide reductase, which catalyzes the conversion of ribonucleosides into deoxyribonucleosides. Adriamycin has a relatively low activation energy and can be activated thermally or photolytically.

Chemical properties

• Molecular weight: 420.41 g/mol
• Formula: C₂₀H₂₄N₂O₈
• Purity: Min. 95%
• Color/Form: Powder