Beclomethasone 17-propionate

CAS: 5534-18-9

Ref. 3D-FB18152

Product Information

• Name: Beclomethasone 17-propionate
• Synonyms: (11β,16β)-9-Chloro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione
• Brand: Biosynth
• Description: Beclomethasone 17-propionate is a corticosteroid that inhibits the inflammatory response by binding to the glucocorticoid receptor. It has been shown to inhibit the production of pro-inflammatory cytokines and chemokines, such as colony-stimulating factor (CSF), in lung cells and to have an inhibitory effect on microbial biotransformation. Beclomethasone 17-propionate can be used to treat bronchial asthma, chronic obstructive pulmonary disease, and other respiratory diseases. The drug is rapidly absorbed into the cell culture after inhalation and has a high uptake rate. However, it is not active when given orally due to its poor solubility in water or lipid membranes. Beclomethasone 17-propionate also binds to matrix proteins in the lungs, which may account for its long duration of action.

Chemical properties

• Molecular weight: 464.98 g/mol
• Formula: C₂₅H₃₃ClO₆
• Purity: Min. 95%
• Color/Form: White Powder