Benfotiamine

CAS: 22457-89-2

Ref. 3D-FB18169

Product Information

• Name: Benfotiamine
• Synonyms: Benzenecarbothioic acid S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]fo rmylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl]esterBenzoylthiamine monophosphate
• Brand: Biosynth
• Description: Benfotiamine is a thiamine derivative that is structurally similar to thiamine. It has been shown to have pharmacological effects in experimental models of diabetic complications and may be a potential therapeutic agent for the treatment of these conditions. Benfotiamine binds to the response element on the nuclear DNA, which leads to an increase in calcium pantothenate, a cofactor necessary for energy metabolism in mitochondria. The enzyme activities of benfotiamine are also modulated by calcium and magnesium ions. Benfotiamine can be used as an analytical method for nonsteroidal anti-inflammatory drugs (NSAIDs) by measuring the levels of benzoquinone imines and fluoroquinolones in urine.

Chemical properties

• Molecular weight: 466.45 g/mol
• Formula: C₁₉H₂₃N₄O₆PS
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C19H23N4O6PS/c1-13(23(12-24)11-16-10-21-14(2)22-18(16)20)17(8-9-29-30(26,27)28)31-19(25)15-6-4-3-5-7-15/h3-7,10,12H,8-9,11H2,1-2H3,(H2,20,21,22)(H2,26,27,28)/b17-13-
• InChI key: InChIKey=BTNNPSLJPBRMLZ-LGMDPLHJSA-N
• SMILES: C/C(=C(\CCOP(=O)(O)O)SC(=O)c1ccccc1)N(C=O)Cc1cnc(C)nc1N