Benzylmalonic acid

CAS: 616-75-1

Ref. 3D-FB18395

Product Information

• Name: Benzylmalonic acid
• Synonyms: 2-(Phenylmethyl)propanedioic acid2-Phenyl-1,1-ethanedicarboxylic acid2-Benzylmalonic acid, (Cyclohexylmethyl)Propanedioate, 1,1-Ethanedicarboxylic acid, 2-phenyl-, 2-(Phenylmethyl)propanedioic acid, 2-Benzylmalonate, 2-Benzylmalonic acid, 2-Benzylpropanedioic acid, Ai3-23865, Benzomalonate acid, Benzylpropanedioic Acid, Brn 0643530, Malonic acid, 2-benzyl-, Malonic acid, benzyl-, Nsc 8068, Propanedioic acid, (phenylmethyl)-, Propanedioic acid, (phenylmethyl)- (9CI), Propanedioic acid, 2-(phenylmethyl)-, Usaf Xr-36, 4-09-00-03357 (Beilstein Handbook Reference)

Description

Benzylmalonic acid is a chemical that has been used to study the role of ATP-binding cassette transporter (ABC) proteins in autoimmune diseases. ABC proteins are involved in transporting molecules across cell membranes, and their dysfunction leads to the development of autoimmune diseases. Benzylmalonic acid binds to the receptor site on ABC proteins and blocks their function, inhibiting the production of inflammatory cytokines. This agent also binds to picolinic acid, which is an intermediate metabolite in the kynurenine pathway that is linked to inflammatory response. The structure of benzylmalonic acid may be responsible for its effects on congestive heart disease because it can bind with phosphorus pentoxide and form a precipitate that may interfere with calcium binding. This drug has also shown anti-inflammatory properties as well as cardiotoxic effects when used at high doses.

• Brand: Biosynth

Chemical properties

• Molecular weight: 194.18 g/mol
• Formula: C₁₀H₁₀O₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C10H10O4/c11-9(12)8(10(13)14)6-7-4-2-1-3-5-7/h1-5,8H,6H2,(H,11,12)(H,13,14)
• InChI key: InChIKey=JAEJSNFTJMYIEF-UHFFFAOYSA-N
• SMILES: O=C(O)C(Cc1ccccc1)C(=O)O