Bexarotene

CAS: 153559-49-0

Ref. 3D-FB18579

Product Information

• Name: Bexarotene
• Synonyms: 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic acidLG 100069LG 1069, 1-Bexarotene, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic Acid, SR-11247, LGD-1069, Targretin, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid, Benzoic acid, 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-, LG 69 (retinoid), Lg 100069, Lg 1069, Lg 69, Lgd 1069, Lgd1069, Ro 26-4455, Sr 11247, Targret, Targretin, Targretyn, Targrexin

Description

Selective agonist of retinoid X receptor (RXR), permeable to blood-brain barrier and neuroprotective against neurological pathologies such as subarachnoid haemorrhage, traumatic brain injury, ischemic stroke and Alzheimer’s disease. Bexarotene promoted neurogenesis as a treatment of embryonic stem cells affected proliferation of neural progenitors, neuronal differentiation and stimulated neurite outgrowth.

• Brand: Biosynth

Chemical properties

• Molecular weight: 348.48 g/mol
• Formula: C₂₄H₂₈O₂
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
• InChI key: InChIKey=NAVMQTYZDKMPEU-UHFFFAOYSA-N
• SMILES: C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C