Bis(2-chloroethyl)aminophosphoric dichloride

CAS: 127-88-8

Ref. 3D-FB18667

Product Information

• Name: Bis(2-chloroethyl)aminophosphoric dichloride
• Synonyms: N,N-Bis(2-chloroethyl)phosphoramidic dichlorideN,N-Bis(2-chloroethyl)phosphamide dichlorideBis(2-chloroethyl)phosphoramidic dichlo ride, (N,N-Di-2-chloroethyl) phosphoramidic dichloride, 2-Chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine, Bis(2-chloroethyl)aminophosphonic dichloride, Bis(2-chloroethyl)aminophosphoryl dichloride, N,N-Bis(2-chloroethyl)phosphamide dichloride, N,N-Bis(2-chloroethyl)phosphoramidic dichloride, NSC 64119, Phosphoramidic dichloride, N,N-bis(2-chloroethyl)-, Phosphoramidic dichloride, bis(2-chloroethyl)-

Description

Bis(2-chloroethyl)aminophosphoric dichloride is a fatty acid ester that is used as an antibiotic. It binds to the fatty acid of the bacterial cell membrane, thereby inhibiting the production of vital cell components. Bis(2-chloroethyl)aminophosphoric dichloride has been shown to be active against chondrosarcoma cells in rats and tumor tissue in mice. This drug also inhibits bacterial growth by binding to the fatty acids on the surface of Gram-positive bacteria, such as subtilis and staphylococci. Bis(2-chloroethyl)aminophosphoric dichloride has been shown to have antibacterial activity against Gram-negative bacteria, including Escherichia coli and Salmonella enterica serotype Typhimurium. The binding constants for this drug are high for both Gram-positive and Gram-negative bacteria; however, it does not bind to sugar alcohols or l12

• Brand: Biosynth

Chemical properties

• Molecular weight: 258.9 g/mol
• Formula: C₄H₈Cl₄NOP
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C4H8Cl4NOP/c5-1-3-9(4-2-6)11(7,8)10/h1-4H2
• InChI key: InChIKey=IQPMYTNILJQKBS-UHFFFAOYSA-N
• SMILES: O=P(Cl)(Cl)N(CCCl)CCCl