6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one

CAS: 179688-29-0

Ref. 3D-FB18678

Product Information

• Name: 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one
• Synonyms: 6,7-Di(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one6,7-Bis(2-methoxyethoxy)quinazolin-4(3H)-oneCP-380736, 4(1H)-Quinazolinone, 6,7-bis(2-methoxyethoxy)-, 4(3H)-Quinazolinone, 6,7-bis(2-methoxyethoxy)-, 6,7-Bis(2-Methoxyethoxy)-3,4-Dihydroquinazolin-4-One, 6,7-Bis(2-Methoxyethoxy)Quinazolin-4(1H)-One, 6,7-Bis(2-methoxyethoxy)-quinazoline-4(3H)-one, 6,7-Bis-(2-Methoxyethoxy)-4(3H)-Quinazolinone, 6,7-Di(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-bis(2-methoxyethoxy)-1H-quinazolin-4-one, Erlotinib'S Intermediate, Methyl Ester, 2-Amino-4,5-Bis(2-Methoxyethoxy)Benzoic Acid

Description

This compound is a synthetic molecule that has been shown to have growth factor activity and may be useful in cancer research. The molecule is a nucleophile and reacts with epidermal growth factor (EGF) to form the corresponding adduct. This adduct can then react with chloride to form the corresponding chloro-adduct. It also binds to cellular proteins, such as antigen and factor receptors. The piperazine ring of this molecule is responsible for its binding affinity for these receptors.
The compound was expressed from a plasmid under normoxic conditions, but was not expressed under hypoxic conditions.

• Brand: Biosynth

Chemical properties

• Molecular weight: 294.3 g/mol
• Formula: C₁₄H₁₈N₂O₅
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• InChI key: InChIKey=PMQWTUWLIGJTQD-UHFFFAOYSA-N
• SMILES: COCCOc1cc2nc[nH]c(=O)c2cc1OCCOC