6a-Bromo androstenedione
CAS: 61145-67-3
Ref. 3D-FB19020
2mg | To inquire | ||
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire |
Product Information
- (6a)-6-Bromoandrost-4-ene-3,17-dione
- 6α-Bromo-androstenedione
6a-Bromo androstenedione is a nonsteroidal, non-aromatizable, competitive inhibitor of aromatase. It binds to the active site of the enzyme and blocks the conversion of testosterone to estradiol. 6a-Bromo androstenedione has been shown to inhibit aromatase activity in vitro at an IC50 of about 5 nM. The affinity for the enzyme is about 10 times higher than that for aminoglutethimide, which is another competitive inhibitor of aromatase. 6a-Bromo androstenedione has also been shown to have inhibitory activity against estrogen synthetase in rats.
Chemical properties
Technical inquiry about: 3D-FB19020 6a-Bromo androstenedione
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