4-(2-Bromoacetyl)benzoic acid

Ref. 3D-FB19186

Product Information

• Name: 4-(2-Bromoacetyl)benzoic acid
• Synonyms: 2-Bromo-4'-(hydroxycarbonyl)acetophenone4-(2-Bromoacetyl)benzoic acid4-(Bromoacetyl)benzoic acid
• Brand: Biosynth
• Description: 4-(2-Bromoacetyl)benzoic acid is a chiral and reactive reagent that is used in organic synthesis. The steric bulk of 4-(2-bromoacetyl)benzoic acid allows it to inhibit the activity of enzymes, such as peptidases and esterases. It has been shown to inhibit the enzyme activity of phenacyl esterase with a half maximal inhibitory concentration (IC50) of 0.06 mM, which is considerably less than that for phenacyl itself (1 mM). 4-(2-Bromoacetyl)benzoic acid also reacts with alkylate to form an acetate ester, which can be monitored kinetically by measuring the increase in absorbance at 280 nm.

Chemical properties

• Molecular weight: 243.05 g/mol
• Formula: C₉H₇BrO₃
• Purity: Min. 95%
• Color/Form: White/Off-White Solid
• InChI: InChI=1S/C9H7BrO3/c10-5-8(11)6-1-3-7(4-2-6)9(12)13/h1-4H,5H2,(H,12,13)
• InChI key: InChIKey=ZMHLKKVZTJBBHK-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc(C(=O)CBr)cc1