Bufalin
CAS: 465-21-4
Ref. 3D-FB19349
| 10mg | 180.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 863.00 € | ||
| 250mg | 1,449.00 € |
Product Information
- (3β,5β)-3,14-Dihydroxy-bufa-20,22-dienolide3β,14-dihydroxy-5β-bufa-20,22-dienolide
- (3Beta,5Beta,8Xi,9Xi)-3,14-Dihydroxybufa-20,22-Dienolide
- (3β,5β)-3,14-Dihydroxybufa-20,22-dienolide
- 3,14-Dihydroxybufa-20,22-Dienolide
- 5β-Bufa-20,22-dienolide, 3β,14-dihydroxy-
- B 0261
- Bufa-20,22-dienolide, 3,14-dihydroxy-, (3β,5β)-
- NSC 89595
Bufalin is a natural plant product that has been found to have anti-cancer properties. It inhibits the expression of pro-apoptotic protein in human osteosarcoma cells and induces cell death by apoptosis. This compound also has an inhibitory effect on the α1 subunit of MMP-9, which is a key enzyme in the proteolytic pathway involved with cancer metastasis. Bufalin also exhibits antioxidant and anti-inflammatory activities, which are due to its ability to inhibit the activity of ubiquitin ligases. Bufalin is a plant alkaloid that can be found in plants such as Commiphora wightii and Croton lechleri.
Chemical properties
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