Buformin hydrochloride

CAS: 1190-53-0

Ref. 3D-FB19350

Product Information

• Name: Buformin hydrochloride
• Synonyms: N-Butylimidodicarbonimidic diamide hydrochloride1-Butylbiguanide hydrochloride, 1-Butyl-biguanid hydrochlorid, 1-Butyl-biguanid hydrochlorid [German], 1-Butylbiguanide hydrochloride, 1-Butyldiguanide hydrochloride, 2-Butyl-1-(Diaminomethylidene)Guanidine Hydrochloride (1:1), Adebit, Andere, Biforon, Biguanide, 1-butyl-, hydrochloride, Biguanide, 1-butyl-, monohydrochloride, Bigunal, Bufonamin, Buformine HCl, Bulbonin, Butyl guanylguanidine, Butylbiguanide hydrochloride, DBV hydrochloride, Diabrin, Dibetos, Glibutide, Gliporal, Glybutide, Imidodicarbonimidic diamide, N-butyl-, hydrochloride (1:1), Imidodicarbonimidic diamide, N-butyl-, monohydrochloride, Insulamin, Krebon, N(sup 1)-n-Butylbiguanide hydrochloride, N-Butyl-imidodicarbonimidic diamide monohydrochloride (9CI), N-Butylbiguanide hydrochloride, N¹-Butyl-biguanide hydrochloride, N¹-n-Butylbiguanide hydrochloride, Nsc 113665, Nsc 528218, Panformin, Sb 103, Silubin, Sindiatil, Tidemol, W37, Ziavetine

Description

Buformin hydrochloride is an oral hypoglycemic drug that belongs to the group of biguanides. It is used for the treatment of type 2 diabetes mellitus and has been shown to have a hypoglycemic effect in patients with breast cancer. The mechanism of action of buformin hydrochloride is not fully understood, but it may involve the regulation of mitochondrial membrane potential and transcription activators. Buformin hydrochloride has been shown to decrease the number of lymphocytes, which are responsible for immune responses. This drug also inhibits the growth of c. glabrata, an opportunistic fungal pathogen, by disrupting energy metabolism. Buformin hydrochloride is metabolized in humans and animals by glucuronidation or sulfation. In analytical studies, benzalkonium chloride (BAK) was used as a crystalline cellulose carrier to increase solubility and stability.

• Brand: Biosynth

Chemical properties

• Molecular weight: 193.68 g/mol
• Formula: C₆H₁₆ClN₅
• Purity: Min. 95%
• Color/Form: White Powder