Bumetanide

CAS: 28395-03-1

Ref. 3D-FB19354

Product Information

• Name: Bumetanide
• Synonyms: 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxy-benzoic acid3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acidBufenox, 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid, 3-(Butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, 3-n-Butylamino-4-phenoxy-5-sulfamoylbenzoic acid, Benzoic acid, 3-(butylamino)-4-phenoxy-5-sulfamoyl-, Bufenox, Bumetanid, Bumetanida, Bumethanide, Bumex, Burinex, Edemex, Fontego, Fordiuran, Lixil, Lunetoron, Pf 1593, Ro 10-6338

Description

Bumetanide is a diuretic that inhibits the response of the airways to bronchoconstrictor drugs. It has been shown to inhibit the production of IL-2 receptor in human serum and cytosolic Ca2+ release from cells, leading to neuronal death. Bumetanide also inhibits axonal growth and whole-cell recordings in rat neurons. In addition, bumetanide has been shown to have inhibitory binding on pharmacological agents that are used for congestive heart failure treatment.

• Brand: Biosynth

Chemical properties

• Molecular weight: 364.42 g/mol
• Formula: C₁₇H₂₀N₂O₅S
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)
• InChI key: InChIKey=MAEIEVLCKWDQJH-UHFFFAOYSA-N
• SMILES: CCCCNc1cc(C(=O)O)cc(S(N)(=O)=O)c1Oc1ccccc1