N-Benzyloxycarbonyl-L-leucine

CAS: 2018-66-8

Ref. 3D-FB36690

Product Information

• Name: N-Benzyloxycarbonyl-L-leucine
• Synonyms: (2S)-2-[[(Benzyloxy)carbonyl]amino]-4-methylpentanoic acid, (2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanoate, (2S)-4-Methyl-2-(phenylmethoxycarbonylamino)pentanoic acid, (Benzyloxycarbonyl)leucine, (Carbobenzoxy)leucine, (Carbobenzyloxy)-<span class="text-smallcaps">L</span>-leucine, <span class="text-smallcaps">L</span>-(Carbobenzyloxy)leucine, <span class="text-smallcaps">L</span>-Leucine, N-[(phenylmethoxy)carbonyl]-, <span class="text-smallcaps">L</span>-N-(Benzyloxycarbonyl)leucine, Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-leucine, CBZ-<span class="text-smallcaps">L</span>-leucine, Carbobenzoxy-<span class="text-smallcaps">L</span>-leucine, Cbz-L-leucine, Leucine, N-carboxy-, N-benzyl ester, Leucine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">L</span>-, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-leucine, N-(Benzyloxycarbonyl)leucine, N-(Carbobenzoxy)leucine, N-Carbobenzoxy-<span class="text-smallcaps">L</span>-leucine, N-Carbobenzyloxy-<span class="text-smallcaps">L</span>-leucine, N-Carboxy-<span class="text-smallcaps">L</span>-leucine N-benzyl ester, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-leucine, N-[(benzyloxy)carbonyl]-D-leucine, N-[(benzyloxy)carbonyl]-L-leucine, N-[(benzyloxy)carbonyl]leucine, N-cbz-l-leucine, NSC 60039, Nα-Benzyloxycarbonyl-L-leucine, Z-Leu-OH, z-Leu, L-Leucine, N-[(phenylmethoxy)carbonyl]-, Leucine, N-carboxy-, N-benzyl ester, L-, N-[(Phenylmethoxy)carbonyl]-L-leucine, Benzyloxycarbonyl-L-leucine

Description

N-Benzyloxycarbonyl-L-leucine is a peptidomimetic that has been shown to be effective against P. aeruginosa. The peptidyl amino group has a nucleophilic character, which allows it to react with the carboxyl group of L-lysine and form an amide bond. N-Benzyloxycarbonyl-L-leucine was found to be effective at low doses in inhibiting the growth of P. aeruginosa, and may also have therapeutic potential for treating lymphocytic leukemia. This compound is racemized into its two stereoisomers, D-N-benzyloxycarbonyl-L-leucine and L-N-benzyloxycarbonyl-L-leucine, which have different effects on cell membranes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 265.31 g/mol
• Formula: C₁₄H₁₉NO₄
• Purity: Min. 98 Area-%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C14H19NO4/c1-10(2)8-12(13(16)17)15-14(18)19-9-11-6-4-3-5-7-11/h3-7,10,12H,8-9H2,1-2H3,(H,15,18)(H,16,17)/t12-/m0/s1
• InChI key: InChIKey=USPFMEKVPDBMCG-LBPRGKRZSA-N
• SMILES: CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O