2-Benzoylbenzoic acid methyl ester

CAS: 606-28-0

Ref. 3D-FB37102

Product Information

• Name: 2-Benzoylbenzoic acid methyl ester
• Synonyms: 2-Benzoyl Benzomethoxycarbonyl, Benzoic acid, 2-benzoyl-, methyl ester, Benzoic acid, o-benzoyl-, methyl ester, Daitocure OB, Genocure MBB, Initiator 1056, Methyl 2-Benzoyl Benzoate, Methyl o-benzoylbenzoate, Methyl-O-benzoyl benzoate, NSC 3797, OBM, Obm 100, Ombb, Omnirad OMBB, Photoinitiator MOBB, Photoinitiator-MBB, Pi Mbb, Runtecure 1056, Sb-Pi 711, Speedcure MBB, o-(Methoxycarbonyl)benzophenone, o-Methyl-benzoyl Benzoate
• CAS: 606-28-0

Description

2-Benzoylbenzoic acid methyl ester (2BABME) is a silicone that is used in the manufacturing of polyurethane foams, sealants, and adhesives. It has been shown to have anti-tumor properties. 2BABME was found to inhibit the proliferation of lung fibroblasts and induce apoptosis via induction of caspase-3/7 activity. The production of reactive oxygen species (ROS) and release of cytochrome C from mitochondria are also important factors in the induction of apoptosis by 2BABME. 2BABME induces apoptosis pathways by activating proapoptotic members of the Bcl-2 family, such as Bid, Bad, and Bax. The cytotoxic effects are enhanced by inhibition of ROS production or inhibition of mitochondrial membrane potential. This chemical is not mutagenic or genotoxic in vitro or in vivo.

• Brand: Biosynth

Chemical properties

• Molecular weight: 240.25 g/mol
• Formula: C₁₅H₁₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C15H12O3/c1-18-15(17)13-10-6-5-9-12(13)14(16)11-7-3-2-4-8-11/h2-10H,1H3
• InChI key: InChIKey=NQSMEZJWJJVYOI-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccccc1C(=O)c1ccccc1