3,5-Bis(trifluoromethyl)aniline
CAS: 328-74-5
Ref. 3D-FB37884
| 10g | Discontinued | ||
| 25g | Discontinued | ||
| 50g | Discontinued | ||
| 100g | Discontinued | ||
| 250g | Discontinued |
Product Information
- 1-Nitro-3,5-Bis(Trifluoromethyl)Benzene
- 3',5'-Bis-(Trifluoromethyl)aniline
- 3,5-Bis Trifluoromethyl acetone
- 3,5-Bis(Trifluoromethyl)-Anilin
- 3,5-Bis(Trifluoromethyl)-Benzenamin
- 3,5-Bis(trifluoromethyl)-
- 3,5-Bis(trifluoromethyl)benzenamine
- 3,5-Bis-trifluoromethyl-phenylamine
- 3,5-Di(trifluoromethyl)aniline
- 3,5-Di(trifluoromethyl)phenylamine
- See more synonyms
- 3,5-Xylidine, alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-
- 3,5-Xylidine, α,α,α,α′,α′,α′-hexafluoro-
- 3,5-Xylidine,a,a,a,a',a',a'-hexafluoro-,a,a,a',a',a'-Hexafluoro-3,5-xylidine
- Benzenamine, 3,5-bis(trifluoromethyl)-
- Bis(trifluoromethyl)aniline
- NSC 3411
- alpha,alpha,alpha,alpha,alpha,alpha-Hexafluoro-3,5-xylidine
- aniline
- α,α,α,α′,α′,α′-Hexafluoro-3,5-xylidine
3,5-Bis(trifluoromethyl)aniline (3,5-BFAA) is a potent inhibitor of Gram-negative bacteria and has been shown to be resistant to colistin. 3,5-BFAA binds to hepg2 cells by an amine group and inhibits the transport properties of the cell membrane. This inhibition leads to a decrease in the intracellular concentration of amines and nucleotide monophosphates. 3,5-BFAA also inhibits bacterial growth by binding to the enzyme hepg2 in an irreversible fashion and inhibiting its activity. The inhibitory activity was found to be dependent on the presence of palladium complexes or azides, with quantum theory predicting that this inhibition occurs through hydrogen bonding interactions. Squaramide is another compound that can bind with hepg2 cells and inhibit their transport properties. 3,5-BFAA also has optical properties that make it useful for imaging purposes.
