Boc-N-methyl-D-leucine

Ref. 3D-FB47463

Product Information

• Name: Boc-N-methyl-D-leucine
• Synonyms: Boc-N-Me-D-Leu-OH
• Brand: Biosynth
• Description: Boc-N-methyl-D-leucine is a macrocyclic peptide that has been shown to bind to the active site of a protein called D-alanyl-D-alanine ligase. The binding of this drug to the enzyme prevents the formation of an ATP molecule, which is required for the catalysis of peptide bond formation. Boc-N-methyl-D-leucine also mimics vancomycin, which is an antibiotic that binds to D-alanyl-D-alanine ligase and inhibits its activity. This drug has been shown to inhibit bacterial growth in vitro and in vivo at micromolar concentrations.

Chemical properties

• Molecular weight: 245.32 g/mol
• Formula: C₁₂H₂₃NO₄
• Purity: Min. 95%