Boc-S-trityl-L-homocysteine

CAS: 201419-16-1

Ref. 3D-FB47898

Product Information

• Name: Boc-S-trityl-L-homocysteine
• Synonyms: Boc-L-HomoCys(Trt)-OH(S)-2-(Boc-amino)-4-tritylsulfanylbutyric acid
• Brand: Biosynth
• Description: Boc-S-trityl-L-homocysteine is a synthetic molecule that is used as a prodrug to introduce the amino acid homocysteine into cells. It has been shown to have anti-cancer and estrogen receptor modulating properties. Boc-S-trityl-L-homocysteine is synthesized by reacting L-homocysteine with diisopropylamino chlorides in the presence of sodium hydroxide, followed by ligation with dicyclohexylcarbodiimide. The compound adopts a centrosymmetric conformation due to the presence of two chiral centers at C3 and C4 positions on the pyridyl ring. The active site consists of an aromatic ring with three substituents, one of which is an amide group. This chemical transformation occurs through a nucleophilic attack by the amide group on an electrophilic carbonyl carbon atom.

Chemical properties

• Molecular weight: 477.62 g/mol
• Formula: C₂₈H₃₁NO₄S
• Purity: Min. 95%
• Color/Form: Powder