2-Bromo-D-phenylalanine

CAS: 267225-27-4

Ref. 3D-FB49213

Product Information

• Name: 2-Bromo-D-phenylalanine
• Synonyms: D-Phe(2-Br)-OHo-Bromo-D-phenylalanine(R)-2-Amino-3-(2'-bromophenyl)propanoic acid, D-2-Bromophenylalanine, (2R)-2-ammonio-3-(2-bromophenyl)propanoate, H-D-Phe(2-Br)-OH

Description

2-Bromo-D-phenylalanine is a precursor of l-DOPA, which is an amino acid that is used in the synthesis of dopamine. It is also used as a diagnostic agent for bladder cancer, where it is taken up by bladder cells and converted to radioactive 2-bromo-3′-deoxyuridine. This radioactive compound can be detected with a high performance liquid chromatography (HPLC) system. In addition, 2-Bromo-D-phenylalanine has been shown to inhibit the acid transporter in tumor cells, making it useful as an oncologic drug.
2 bromo d phenylalanine inhibits the acid transporter in tumor cells, making it useful as an oncologic drug

• Brand: Biosynth

Chemical properties

• Molecular weight: 244.09 g/mol
• Formula: C₉H₁₀BrNO₂
• Purity: Min. 95%
• Color/Form: White To Off-White Solid
• InChI: InChI=1S/C9H10BrNO2/c10-7-4-2-1-3-6(7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m1/s1
• InChI key: InChIKey=JFVLNTLXEZDFHW-MRVPVSSYSA-N
• SMILES: N[C@H](Cc1ccccc1Br)C(=O)O