2-Bromo-4-fluorobenzonitrile
CAS: 36282-26-5
Ref. 3D-FB50744
| 25g | 136.00 € | ||
| 50g | 170.00 € | ||
| 100g | 273.00 € | ||
| 250g | 535.00 € | ||
| 500g | 951.00 € |
Product Information
- 4-Fluoro-2-bromobenzonitrile
- Benzonitrile,2-bromo-4-fluoro-
2-Bromo-4-fluorobenzonitrile is a chemical compound that has the molecular formula C6H5BrF2. It is a competitive inhibitor of chaperones. This molecule also has structural isomers, including 2-bromo-4-fluoroaniline and 2,4-dichlorobenzonitrile. The clinical development of this drug for cancer treatment has been halted due to toxic effects on the heart. However, it was shown in animal studies that 2-bromo-4-fluorobenzonitrile can inhibit the growth of tumour cells in a dose dependent manner with nanomolar concentrations. It is believed that these properties are due to its ability to bind to type 1 receptors and inhibit surfactant sodium dodecyl (SDS) fluorescence.
Chemical properties
Technical inquiry about: 3D-FB50744 2-Bromo-4-fluorobenzonitrile
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