5-Benzyloxygramine

CAS: 1453-97-0

Ref. 3D-FB52458

Product Information

• Name: 5-Benzyloxygramine
• Synonyms: 5-Benzyloxy-3-(dimethylaminomethyl)indole1-[5-(Benzyloxy)-1H-indol-3-yl]-N,N-dimethylmethanamine, 1-[5-(benzyloxy)-1H-indol-3-yl]-N,N-dimethylmethanamine, 1H-Indole-3-methanamine, N,N-dimethyl-5-(phenylmethoxy)-, 5-Benzyloxy-3-(dimethylaminomethyl)indole, 5-benzyloxy-N,N-dimethylamino-3-methylindole, Indole, 5-(benzyloxy)-3-[(dimethylamino)methyl]-, N,N-Dimethyl-5-(phenylmethoxy)-1H-indole-3-methanamine, N-{[5-(Benzyloxy)-1H-indol-3-yl]methyl}-N,N-dimethylamine, NSC 17819, [5-(benzyloxy)-1H-indol-3-yl]-N,N-dimethylmethanaminium

Description

5-Benzyloxygramine is an oxalyl derivative that has been shown to be a substrate for uptake by the acidic 5-hydroxytryptamine (5-HT) transporter. It is also a substrate for acetylcholine esterase and has been used as a pharmacological agent in epileptic patients. 5-Benzyloxygramine is metabolized to 5-hydroxytryptophol, which subsequently undergoes oxidation to serotonin. This drug has been shown to have an affinity for human urinary bladder cells and may act as a stabilizer of this cell type.

• Brand: Biosynth

Chemical properties

• Molecular weight: 280.36 g/mol
• Formula: C₁₈H₂₀N₂O
• Color/Form: Powder
• InChI: InChI=1S/C18H20N2O/c1-20(2)12-15-11-19-18-9-8-16(10-17(15)18)21-13-14-6-4-3-5-7-14/h3-11,19H,12-13H2,1-2H3
• InChI key: InChIKey=POTVAILTNPOQJH-UHFFFAOYSA-N
• SMILES: CN(C)Cc1c[nH]c2ccc(OCc3ccccc3)cc12