3-(4-Bromophenyl)-1-phenylpyrazole-4-carbaldehyde
CAS: 36640-41-2
Ref. 3D-FB54028
| 1g | 517.00 € | ||
| 50mg | 136.00 € | ||
| 100mg | 172.00 € | ||
| 250mg | 232.00 € | ||
| 500mg | 341.00 € |
Product Information
- 1H-Pyrazole-4-carboxaldehyde, 3-(4-bromophenyl)-1-phenyl-
- 3-(4-Bromo-phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
3-(4-Bromophenyl)-1-phenylpyrazole-4-carbaldehyde (3BPPA) is an antitubercular agent that belongs to the group of aryl pyrazoles. It is synthesized by reacting 3-bromoaniline with acetaldehyde, followed by condensation with phenylhydrazine, and subsequent cyclization with sodium hydroxide in ethanol. 3BPPA has antitubercular activity and additionally shows some anti-inflammatory properties. The molecule has a pyrazole ring, which is five membered heterocycle containing two nitrogen atoms in the ring. The pharmacological effects of 3BPPA are mediated through its interaction with protein kinase C and inhibition of cell migration. The orientation of the carbaldehyde group is important for the desired pharmacological effects. The azomethine group on 3BPPA can be oriented either cis or trans to the carbaldehyde group, depending on whether it is attached to the same or
Chemical properties
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