Benzo-12-crown 4-Ether

Ref. 3D-FB62069

Product Information

• Name: Benzo-12-crown 4-Ether
• Synonyms: 2,3-Benzo-1,4,7,10-tetraoxadodec-2-ene
• Brand: Biosynth
• Description: Benzo-12-crown 4-ether is a chemical compound that belongs to the class of benzo crown ethers. It has an optimum concentration of 0.1 M and is soluble in organic solvents such as chloroform, methanol, ethanol, acetone, ethyl acetate, and tetrahydrofuran. Benzo-12-crown 4-ether has been shown to be a potent inhibitor of the tyrosine kinase activity of icotinib hydrochloride (IH) with a binding constant of 1.5 × 10 M. The molecule adopts a rigid structure due to its benzene ring and four ether groups attached to the phenyl group. The molecular weight is 576 g/mol and it has an optical rotation of +27°. FTIR spectroscopy was used to identify functional groups present in this molecule as well as its ring opening in acidic environments at pH 2.; Benzo-12-c

Chemical properties

• Purity: Min. 95%