4,4'-Bis(dimethylamino)benzophenone

CAS: 90-94-8

Ref. 3D-FB63042

Product Information

• Name: 4,4'-Bis(dimethylamino)benzophenone
• Synonyms: Michler's KetoneN,N,N',N'-Tetramethyl-4,4'-diaminobenzophenone
• Brand: Biosynth
• Description: 4,4'-Bis(dimethylamino)benzophenone (4,4'-BDMAB) is an organic molecule that has the potential to cause genotoxic effects at high concentrations. It is a cationic polymerization initiator that has been shown to bind to DNA and inhibit hl-60 cells. 4,4'-BDMAB also reacts with phenoxy groups in nucleotide phosphate chains, forming toxic products. The mechanism of this reaction is not yet clear. Studies have shown that 4,4'-BDMAB can cause cell death by inducing apoptosis as well as necrosis. This molecule can also form ketones through reactions with carbonyl groups in cell culture.

Chemical properties

• Molecular weight: 268.35 g/mol
• Formula: C₁₇H₂₀N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C17H20N2O/c1-18(2)15-9-5-13(6-10-15)17(20)14-7-11-16(12-8-14)19(3)4/h5-12H,1-4H3
• InChI key: InChIKey=VVBLNCFGVYUYGU-UHFFFAOYSA-N
• SMILES: CN(C)c1ccc(C(=O)c2ccc(N(C)C)cc2)cc1