5-Benzyl L-glutamate N-carboxyanhydride

CAS: 3190-71-4

Ref. 3D-FB63140

Product Information

• Name: 5-Benzyl L-glutamate N-carboxyanhydride
• Brand: Biosynth
• Description: 5-Benzyl L-glutamate N-carboxyanhydride is a reactive derivative of L-glutamic acid, where the amino acid has been cyclised as an N-carboxyanhydride (NCA), a class of reagent known as Leuchs’ anhydrides. 5-Benzyl L-glutamate N-carboxyanhydride reacts with nucleophiles such as alcohols and amines to form esters and amides respectively. The opening of the N-carboxyanhydride to an ester or amide releases the amino acid amine which can also react as a nucleophile leading to polymerisation. These poly-amide polymers have been investigated as delivery platforms of Small Interfering RNA (si-RNA).

Chemical properties

• Molecular weight: 263.25 g/mol
• Formula: C₁₃H₁₃NO₅
• Purity: Min. 95 Area-%
• Color/Form: White Off-White Powder