(2S,3R)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate

CAS: 112741-50-1

Ref. 3D-FB63306

Product Information

• Name: (2S,3R)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate
• Synonyms: (2S,3R)-(+)-N-tert-Butoxycarbonyl-6-oxo-2,3-diphenylmorpholine, (5R,6S)-N-Boc-5,6-diphenyl-2-morpholinone, 1,1-Dimethylethyl (2S,3R)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate, 4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, 1,1-dimethylethyl ester, (2S,3R)-, 4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, 1,1-dimethylethyl ester, (2S-cis)-, Tert-Butyl 6-Oxo-2,3-Diphenylmorpholine-4-Carboxylate, tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate, tert-butyl (2S,3R)-6-oxo-2,3-diphenylmorpholine-4-carboxylate

Description

(2S,3R)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate is an enolate that can be used for the preparation of chiral α-amino acids. The enantiomers are racemates and crystallize from water as colorless needles with a melting point of 113°C. The solubility is in chloroform and benzene. Preparation of this compound starts with the reaction between glycine and acetone followed by reduction with sodium borohydride.

• Brand: Biosynth

Chemical properties

• Molecular weight: 353.41 g/mol
• Formula: C₂₁H₂₃NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C21H23NO4/c1-21(2,3)26-20(24)22-14-17(23)25-19(16-12-8-5-9-13-16)18(22)15-10-6-4-7-11-15/h4-13,18-19H,14H2,1-3H3/t18-,19+/m1/s1
• InChI key: InChIKey=MRUKRSQUUNYOFK-MOPGFXCFSA-N
• SMILES: CC(C)(C)OC(=O)N1CC(=O)O[C@@H](c2ccccc2)[C@H]1c1ccccc1