Bergamottin

CAS: 7380-40-7

Ref. 3D-FB65517

Product Information

• Name: Bergamottin
• Synonyms: 4-Geranyloxypsoralen, 4-[[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one, 4-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one, 5-Geranoxypsoralen, 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[(3,7-dimethyl-2,6-octadienyl)oxy]-, (E)-, 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-, 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-3,7-dimethyl-2,6-octadienyl]oxy]-, Bergamotine, Bergaptin

Description

Bergamottin is a natural compound that has been shown to have a range of effects, including DNA binding activity and the ability to induce apoptosis in cells. It induces apoptosis in 3T3-L1 preadipocytes and HL-60 cells by activating caspase-independent cell death. Bergamottin also blocks the process of cell division by inhibiting the synthesis of RNA and protein. This compound has been found to inhibit the activity of drug transporters, such as P-glycoprotein (Pgp) and multidrug resistance proteins. It is also able to inhibit squamous cell carcinomas in animal models.
The molecular weight of bergamottin is 239 g/mol with a pka value of 4.2. The chemical formula for bergamottin is C15H14O6, which can be determined using preparative high performance liquid chromatography (HPLC). The rate constant for bergamottin was

• Brand: Biosynth

Chemical properties

• Molecular weight: 338.4 g/mol
• Formula: C₂₁H₂₂O₄
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-16-7-8-20(22)25-19(16)13-18-17(21)10-12-23-18/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+
• InChI key: InChIKey=DBMJZOMNXBSRED-OQLLNIDSSA-N
• SMILES: CC(C)=CCC/C(C)=C/COc1c2ccoc2cc2oc(=O)ccc12