3-Bromosalicylic acid

CAS: 3883-95-2

Ref. 3D-FB66982

Product Information

• Name: 3-Bromosalicylic acid
• Synonyms: 3-Bromo-2-hydroxybenzoic acid, Benzoic Acid, 3-Bromo-2-Hydroxy-, Salicylic acid, 3-bromo-

Description

3-Bromosalicylic acid is a metabolite of salicylic acid and has shown clinical use in the treatment of cancer. 3-Bromosalicylic acid is synthesized from cyclohexanol and chlorine. It is a toxic compound that has been shown to inhibit protein synthesis in bacteria, including soil bacteria, but not in mammalian cells. This is due to its interaction with organic ligands that are present in the bacterial cell wall and not in mammalian cells. 3-Bromosalicylic acid also has been found to be a ligand for the receptor, PI3Kδ inhibitor, which inhibits tumor growth and metastasis by inhibiting phosphatidylinositol 3-kinase (PI3K) delta activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 217.02 g/mol
• Formula: C₇H₅BrO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H5BrO3/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,9H,(H,10,11)
• InChI key: InChIKey=BHPSQWRVKOPSOQ-UHFFFAOYSA-N
• SMILES: O=C(O)c1cccc(Br)c1O