4-Bromo-3-fluorobenzyl alcohol

CAS: 222978-01-0

Ref. 3D-FB67504

Product Information

• Name: 4-Bromo-3-fluorobenzyl alcohol
• Synonyms: (4-Bromo-3-fluorophenyl)methan-1-ol
• Brand: Biosynth
• Description: 4-Bromo-3-fluorobenzyl alcohol is an analog of prenylation, a process that is essential for the synthesis of many cellular components. It inhibits farnesyltransferase, an enzyme involved in the process of prenylation. Farnesyltransferase catalyzes the conversion of the 5-carbon farnesol to the 15-carbon geranylgeraniol, which is then converted to a 20-carbon geranylgeranyl pyrophosphate. This reaction generates a molecule with two prenyl groups. The discovery of 4-bromo-3-fluorobenzyl alcohol was made possible by its potent inhibition of farnesyltransferase and it has been shown to have promising results as a potential treatment for cancer.

Chemical properties

• Molecular weight: 205.02 g/mol
• Formula: C₇H₆BrFO
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H6BrFO/c8-6-2-1-5(4-10)3-7(6)9/h1-3,10H,4H2
• InChI key: InChIKey=VQDUFYPJCUBGQW-UHFFFAOYSA-N
• SMILES: OCc1ccc(Br)c(F)c1