4-Benzyloxy-3,5-dimethylbenzaldehyde

CAS: 144896-51-5

Ref. 3D-FB69920

Product Information

• Name: 4-Benzyloxy-3,5-dimethylbenzaldehyde
• Synonyms: 3,5-Dimethyl-4-(phenylmethoxy)benzaldehyde, 3,5-Dimethyl-4-benzyloxybenzaldehyde, 4-Benzyloxy-3,5-Dimethylbenzaldehyde, 97 %, 4-Benzyloxy-3,5-dimethylbenzaldehyde, 98+%, Benzaldehyde, 3,5-dimethyl-4-(phenylmethoxy)-

Description

4-Benzyloxy-3,5-dimethylbenzaldehyde is a potent anticancer drug that inhibits cell proliferation and induces apoptosis. It has been shown to inhibit the growth of prostate cancer cells and human erythroleukemia cells. This compound also has antibacterial activity against gram-positive bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. 4-Benzyloxy-3,5-dimethylbenzaldehyde binds to the flavone binding site on the enzyme DNA gyrase and topoisomerase IV in both bacterial and mammalian cells. This binding leads to inhibition of DNA synthesis by preventing the formation of an enzyme complex with DNA polymerase. A study has shown that apigenin, one of the flavone derivatives found in this compound, enhances the antitumor activity of cisplatin by inhibiting DNA repair mechanisms in human cancer cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 240.3 g/mol
• Formula: C₁₆H₁₆O₂
• Purity: 90%
• Color/Form: Powder
• InChI: InChI=1S/C16H16O2/c1-12-8-15(10-17)9-13(2)16(12)18-11-14-6-4-3-5-7-14/h3-10H,11H2,1-2H3
• InChI key: InChIKey=GSYUTKRSEZMBNC-UHFFFAOYSA-N
• SMILES: Cc1cc(C=O)cc(C)c1OCc1ccccc1