2-Bromo-5-methoxybenzoic acid

CAS: 22921-68-2

Ref. 3D-FB70043

Product Information

• Name: 2-Bromo-5-methoxybenzoic acid
• Brand: Biosynth
• Description: 2-Bromo-5-methoxybenzoic acid (BMBA) is a natural compound that belongs to the class of ellagitannins. It has been shown to inhibit the proliferation of leukemia cells and induce apoptosis in these cells. The mechanism of this apoptotic activity may be due to BMBA's inhibition of the progesterone receptor, which has been demonstrated by molecular modeling and 13C NMR spectroscopy experiments. This receptor is involved in cancer development and progression. BMBA also inhibits the mitochondrial membrane potential, leading to cell death. In addition, 2-Bromo-5-methoxybenzoic acid has been shown to have anti-inflammatory properties in mice with chronic colitis. This compound also has an effect on bacteria such as Pseudomonas aeruginosa, which was observed using thermodynamic calculations.

Chemical properties

• Molecular weight: 231.04 g/mol
• Formula: C₈H₇BrO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H7BrO3/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4H,1H3,(H,10,11)
• InChI key: InChIKey=ODHJOROUCITYNF-UHFFFAOYSA-N
• SMILES: COc1ccc(Br)c(C(=O)O)c1