S-Benzylisothiourea hydrochloride

CAS: 538-28-3

Ref. 3D-FB71164

Product Information

• Name: S-Benzylisothiourea hydrochloride
• Synonyms: (Benzylsulfanyl)(imino)methanaminium chloride, (Benzylsulfanyl)methanimidamide hydrochloride, 2-Benzyl-2-Thiopseudourea Hydrochloride, 208-688-6, Benzituron, Benzyl Carbamimidothioate Hydrochloride (1:1), Benzyl carbamimidothioate hydrochloride, Benzyl thiopseudourea hydrochloride, Benzylisothiourea hydrochloride, Benzylisothiouronium chloride, Benzylisothiuronium chloride, Carbamimidothioic Acid Phenylmethyl Ester Monohydrochloride, Carbamimidothioic Acid, Phenylmethyl Ester, Hydrochloride (1:1), Pseudourea, 2-benzyl-2-thio-, hydrochloride, Pseudourea, 2-benzyl-2-thio-, monohydrochloride, Pseudourea, 2-thio-2-benzyl-, hydrochloride, S-Benzylisothiouronium chloride, S-Benzylisothiouronium hydrochloride, S-Benzylisothiuronium chloride, S-Benzylthioformamidine hydrochloride, S-Benzylthiopseudourea hydrochloride, S-Benzylthiourea hydrochloride, S-Benzylthiouronium chloride, S-Benzylthiuronium chloride, U 19451A

Description

S-Benzylisothiourea hydrochloride (SBIT) is a potent inhibitor of the influenza virus by binding to the polymerase domain of the virus’s RNA-dependent RNA polymerase. SBIT inhibits viral transcription and replication, as well as viral assembly, release, and infectivity. SBIT has been shown to inhibit avian influenza A/H5N1 in cell culture and in mice models with no observable adverse effects. The mechanism of action for this drug is not yet understood but may be related to its ability to inhibit the kinase domain of avian influenza NS1 protein which is involved in regulating inflammatory responses.

• Brand: Biosynth

Chemical properties

• Molecular weight: 202.71 g/mol
• Formula: C₈H₁₀N₂S·HCl
• Purity: Min. 95%
• Color/Form: Powder