7-Bromo-L-tryptophan

CAS: 75816-19-2

Ref. 3D-FB76581

Product Information

• Name: 7-Bromo-L-tryptophan
• Synonyms: 7-Chloro-4-hydroxyquinoline-2-carboxylic acid, 7-Cl-KYNA, 7-Chloro-4-Hydroxy-2-Carboxyquinoline, 7-Chlorokynurenic acid

Description

7-Bromo-L-tryptophan is an amino acid that belongs to the class of aromatic compounds. It can be produced by the cross-coupling reaction of 7-bromoindole and L-tryptophan in aqueous solution. The biosynthesis of 7-bromo-L-tryptophan is achieved by corynebacterium glutamicum, which is a gram negative bacterium. This strain contains two genes encoding enzymes required for this process: anthranilate synthase and dehydrogenase. 7-Bromo L-tryptophan can be converted into anthranilic acid with high yield (>90%) at neutral pH; however, it is only active at acidic pH (pH 2). This compound has been used in a bioassay as a substrate for growth rate determination of corynebacterium strains.

• Brand: Biosynth

Chemical properties

• Molecular weight: 283.12 g/mol
• Formula: C₁₁H₁₁BrN₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H11BrN2O2/c12-8-3-1-2-7-6(5-14-10(7)8)4-9(13)11(15)16/h1-3,5,9,14H,4,13H2,(H,15,16)/t9-/m0/s1
• InChI key: InChIKey=VMMOOBBCGTVDGP-VIFPVBQESA-N
• SMILES: N[C@@H](Cc1c[nH]c2c(Br)cccc12)C(=O)O