5-Chlorouracil

CAS: 1820-81-1

Ref. 3D-FC05961

Product Information

• Name: 5-Chlorouracil
• Synonyms: 5-Chloro-2,4-dihydroxypyrimidine, 2,4(1H,3H)-Pyrimidinedione, 5-chloro-, 5-Chloro-2,4(1H,3H)-pyrimidinedione, 5-Chloro-2,4-pyrimidinedione, 5-Chloropyrimidine-2,4-diol, 5-chloropyrimidine-2,4(1H,3H)-dione, Ai3-26560, Nsc 28172, Uracil, 5-chloro-, Uracil, 5-chloro- (VAN)

Description

5-Chlorouracil is a drug that is used to treat cancer. It has been shown to have biological properties, and its mechanism of action is not yet fully understood. 5-Chlorouracil can be synthesized in the laboratory by reacting sodium hydroxide with 5-chloro-2,4(1H,3H)-pyrimidinedione. In wastewater treatment plants, it reacts with organic matter in the water to form nontoxic products, such as carbon dioxide and urea. The reaction solution contains 5-chlorouracil, which undergoes tautomerization spontaneously or through the addition of base. This reaction is reversible, and both the erythro and threo forms are present in solution at equilibrium. The biological properties of 5-chlorouracil have been investigated using sublethal doses in experimental animals. In one study, 5-chlorouracil was found to inhibit xanthine oxidase activity in rats significantly more

• Brand: Biosynth

Chemical properties

• Molecular weight: 146.53 g/mol
• Formula: C₄H₃ClN₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C4H3ClN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
• InChI key: InChIKey=ZFTBZKVVGZNMJR-UHFFFAOYSA-N
• SMILES: O=c1[nH]cc(Cl)c(=O)[nH]1