5-Chloro-2-methoxycarbonyl pyrazine

CAS: 33332-25-1

Ref. 3D-FC06065

Product Information

• Name: 5-Chloro-2-methoxycarbonyl pyrazine
• Synonyms: Methyl 5-chloropyrazine-2-carboxylate5-Chloropyrazine-2-carboxylic acid methyl ester, 5-Chloro-Pyrazine-2-Carboxylic Acid Methyl Ester, Pyrazinecarboxylic Acid, 5-Chloro-,Methyl Ester, 5-Chloro-2-Pyrazinecarboxylic Acid Methyl Ester, Methyl-5-Chloro-2-Pyrazinecarboxylate, 5-Chloropyrazine-2-Methylcarboxylate, Methyl 5-Chloropiperazine-2-Carbonate, 5-Chloro-2-Methoxycarbonylpyrazine, 1-Phenylcyclopropanamine Hydrochloride, Ethyl 3-Aminobicyclo[2.2.1]Hept-5-Ene-2-Carboxylate, Ethyl (1R,2S,3R,4S)-3-Aminobicyclo[2.2.1]Hept-5-Ene-2-Carboxylate

Description

5-Chloro-2-methoxycarbonyl pyrazine is a linker that is used to connect two pharmacophores. β-Lactamase, which is an enzyme that degrades β-lactams antibiotics, was inhibited by 5-chloro-2-methoxycarbonyl pyrazine in vitro and in vivo. The inhibitory potency of 5-chloro-2-methoxycarbonyl pyrazine was increased when it was combined with other molecules. This molecule has shown antibacterial activity against Enterobacter cloacae, methicillin resistant Staphylococcus aureus (MRSA), and Mycobacterium tuberculosis.

5-Chloro-2-methoxycarbonyl pyrazine has also been shown to have potent inhibitory properties on the medulloblastoma cell line SHSY5Y, which are primarily due to its ability to inhibit

• Brand: Biosynth

Chemical properties

• Molecular weight: 172.57 g/mol
• Formula: C₆H₅ClN₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C6H5ClN2O2/c1-11-6(10)4-2-9-5(7)3-8-4/h2-3H,1H3
• InChI key: InChIKey=CVVMLRFXZPKILB-UHFFFAOYSA-N
• SMILES: COC(=O)c1cnc(Cl)cn1