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6-Chloro-3-aminopyridine-2-carboxamide

CAS:

Ref. 3D-FC07007

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6-Chloro-3-aminopyridine-2-carboxamide
Biosynth

Product Information

Name:6-Chloro-3-aminopyridine-2-carboxamide
Brand:Biosynth
Description:6-Chloro-3-aminopyridine-2-carboxamide is a small molecule that inhibits tumor growth in human prostate cancer cells. It binds to a pharmacophore, which is a three dimensional arrangement of atoms that is responsible for the biological activity of the drug. This compound has been shown to inhibit tumor cell proliferation and induce apoptosis. 6-Chloro-3-aminopyridine-2-carboxamide also inhibits the oncogenic signaling pathways, including the PI3K/Akt and MAPK pathways, leading to antiproliferative activity in cancer cell lines. 6-Chloro-3-aminopyridine-2-carboxamide also inhibits phosphorylation of Akt and Erk1/2, which are downstream targets of PI3K/Akt pathway activation. The compound was found to have no significant effects on noncancerous cells or normal prostate tissue.
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Chemical properties

Molecular weight:171.58 g/mol
Formula:C6H6ClN3O
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C6H6ClN3O/c7-4-2-1-3(8)5(10-4)6(9)11/h1-2H,8H2,(H2,9,11)
InChI key:InChIKey=ZGGQDDSXBIALBC-UHFFFAOYSA-N
SMILES:NC(=O)c1nc(Cl)ccc1N

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