8-Chloroguanine

CAS: 22052-03-5

Ref. 3D-FC08629

Product Information

• Name: 8-Chloroguanine

Description

8-Chloroguanine is a carcinogen that has been shown to cause cancer in laboratory animals. It is a reactive compound with a hydroxyl group and a hydrogen bond that can react with DNA, leading to the formation of 8-chloroadenine (8-CAD) and 8-chloroguanine (8-CG). These compounds are then converted into hypochlorous acid, which has been shown to be an inflammatory agent. The analytical method for quantifying 8-chloroguanine can be done by electrochemical impedance spectroscopy. This method has been used in model studies of inflammatory diseases.

• Brand: Biosynth

Chemical properties

• Molecular weight: 185.57 g/mol
• Formula: C₅H₄ClN₅O
• Purity: Min. 95 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C5H4ClN5O/c6-4-8-1-2(9-4)10-5(7)11-3(1)12/h(H4,7,8,9,10,11,12)
• InChI key: InChIKey=YCFWZXAEOXKNHL-UHFFFAOYSA-N
• SMILES: Nc1nc2nc(Cl)[nH]c2c(=O)[nH]1