3-Cyano-2-hydroxypyridine

CAS: 20577-27-9

Ref. 3D-FC09747

Product Information

• Name: 3-Cyano-2-hydroxypyridine
• Synonyms: 2-Hydroxy-3-cyanopyridine, 1,2-Dihydro-2-oxo-3-pyridinecarbonitrile, 1,2-Dihydro-2-oxopyridine-3-carbonitrile, 1,2-Dihydropyridine-2-oxo-3-carbonitrile, 2-Hydroxy-3-Pyridinecarbonitrile, 2-Hydroxy-Nicotinonitrile, 2-Hydroxynicotinonitrile, 2-Hydroxypyridine-3-carbonitrile, 2-Oxo-1,2-Dihydropyridine-3-Carbonitrile, 2-Oxo-1,2-dihydro-3-pyridinecarbonitrile, 2-Oxo-1H-pyridine-3-carbonitrile, 3-Cyano-1H-pyridin-2-one, 3-Cyano-2(1H)-Pyridinone, 3-Cyano-2-Hydroxypyridine, 3-Cyano-2-pyridinol, 3-Cyano-2-pyridone, 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-, 3-Pyridinecarbonitrile, 2-hydroxy-, Nicotinonitrile, 1,2-dihydro-2-oxo-

Description

3-Cyano-2-hydroxypyridine is an inhibitor of the noradrenaline transporter, which is a type of l-type calcium channel. 3-Cyano-2-hydroxypyridine has been shown to be a potent inhibitor of the noradrenaline transporter. It inhibits the binding of neurotransmitters to their receptors by blocking active methylene sites on the transporter molecule. This drug also has a cavity that can accommodate bulky inhibitor molecules, making it more difficult for these inhibitors to bind to the active site and compete with neurotransmitters for uptake. 3Cyano-2-hydroxypyridine also inhibits nitric oxide synthase, which may provide anti-tumor activity as well as inhibit tumor cell growth. The inhibitory effect of this drug is due to structural studies that have revealed hydrogen bonding interactions with the drug's nitrogen and oxygen atoms.

• Brand: Biosynth

Chemical properties

• Molecular weight: 120.11 g/mol
• Formula: C₆H₄N₂O
• Purity: Min. 95%
• Color/Form: Yellow To Brown Solid