7-Chloro-5-(2-fluorophenyl)-1,3-Dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one

CAS: 49606-44-2

Ref. 3D-FC101766

Product Information

• Name: 7-Chloro-5-(2-fluorophenyl)-1,3-Dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one
• Synonyms: 2- Desthio- 2- oxo Selapam
• Brand: Biosynth
• Description: Quazepam is a benzodiazepine drug that binds to the benzodiazepine binding site of the GABAA receptor. It has clinical properties as an anxiolytic and anticonvulsant. Quazepam has been determined to have a high affinity for the benzodiazepine binding site in human liver, plasma, and brain tissue. The kinetic data for quazepam show that it is metabolized by oxidation and hydrolysis, which result in two metabolites: N-desmethyldiazepam and oxazepam. Quazepam is also shown to induce sleep, even at doses of 25 mg or less per day. The clinical properties of quazepam are similar to those of other benzodiazepines with a short half-life such as triazolam. However, it does not have significant drug interactions with other drugs like triazolam does.

Chemical properties

• Molecular weight: 370.73 g/mol
• Formula: C₁₇H₁₁ClF₄N₂O
• Purity: Min. 98 Area-%
• Color/Form: Solid
• InChI: InChI=1S/C17H11ClF4N2O/c18-10-5-6-14-12(7-10)16(11-3-1-2-4-13(11)19)23-8-15(25)24(14)9-17(20,21)22/h1-7H,8-9H2
• InChI key: InChIKey=YFSXBSRGIRSXAD-UHFFFAOYSA-N
• SMILES: O=C1CN=C(c2ccccc2F)c2cc(Cl)ccc2N1CC(F)(F)F