1-Cyano-2-hydroxy-3-butene
CAS: 27451-36-1
Ref. 3D-FC10557
| 10mg | 95.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 228.00 € | ||
| 100mg | 384.00 € | ||
| 250mg | 660.00 € |
Product Information
- 3-Hydroxy-4-pentenenitrileCyanohydroxybuteneCHP
- (3S)-3-hydroxypent-4-enenitrile
- 2-Hydroxy-3-butenyl cyanide
- 3-Hydroxy-4-cyano-1-butene
- 3-Hydroxy-4-pentenenitrile
- 4-Pentenenitrile, 3-Hydroxy-
- Cyanohydroxybutene
1-Cyano-2-hydroxy-3-butene is a mitochondrial toxin that causes apoptosis in liver cells. It has been shown to cause liver lesions in CD1 mice. 1-Cyano-2-hydroxy-3-butene reduces the mitochondrial membrane potential, which leads to a decrease in ATP production and an increase in reactive oxygen species (ROS) production. This toxin also inhibits the transcriptional activity of nuclear receptors and induces the expression of cytochrome P450 2E1, leading to increased detoxification enzyme activity. 1-Cyano-2-hydroxy-3-butene is activated by mitochondria, which leads to its ability to cause apoptosis of liver cells.
Chemical properties
Technical inquiry about: 3D-FC10557 1-Cyano-2-hydroxy-3-butene
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