Product Information
Name:Cyclohexylstatine
Synonyms:
- (3S,4S)-4-Amino-5-cyclohexyl-3-hydroxy-pentanoic acid
- ACHPA
Brand:Biosynth
Description:Cyclohexylstatine is a glycopeptide antibiotic that inhibits the synthesis of collagen in animals and humans. It also has been shown to have anticancer activity. Cyclohexylstatine works by inhibiting the biosynthesis of collagen, which is an important component of skin, ligaments, and tendons. The molecule was synthesized in 1975 and has been used as a pharmaceutical agent since 1980. Cyclohexylstatine is the first anti-collagen drug to be developed for use in humans. It has been shown to be effective against autoimmune diseases such as rheumatoid arthritis but not against cancer cells or bacteria. Cyclohexylstatine binds to the zymogen form of collagenase and inhibits its activity. This inhibition leads to an accumulation of polysaccharides in the extracellular matrix that are converted into oligosaccharides by glycosidases present in tissue fluids. These oligosaccharides inhibit collagen synthesis by binding to
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Chemical properties
Molecular weight:215.29 g/mol
Formula:C11H21NO3
Purity:Min. 95%
Technical inquiry about: Cyclohexylstatine
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