Product Information
Name:CRF (6-33) (human, rat)
Synonyms:
- H-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-OH H-ISLDLTFHLLRE VLEMARAEQLAQQAHS-OH
Brand:Biosynth
Description:CRF (6-33) is a neuropeptide that is found in the human cerebral cortex and rat liver. It has been shown to inhibit protein synthesis and sequenced by Edmond H. Fischer, who also discovered corticotropin-releasing factor (CRF). CRF (6-33) binds to its receptor CRFR1, which activates phospholipase C and generates inositol 1,4,5-triphosphate. This leads to the release of calcium from intracellular stores and the activation of protein kinase C. The release of calcium ions into the cytosol causes an increase in intracellular levels of cAMP, which activates a series of reactions responsible for the cellular effects of CRF. CRF (6-33) has been shown to be involved in depression by controlling neurotransmitter levels.br>
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:3,220.66 g/mol
Formula:C141H231N41O43S
Purity:Min. 95%
Technical inquiry about: CRF (6-33) (human, rat)
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