Caspase-3/7 Inhibitor II Ac-Asp-Asn-Leu-Asp-aldehyde (pseudo acid)
CAS: 775289-20-8
Ref. 3D-FC111120
2mg | 322.00 € | ||
5mg | 539.00 € | ||
10mg | 871.00 € | ||
25mg | 1,639.00 € | ||
50mg | 2,854.00 € |
Product Information
- Ac-DNLD-CHO
Caspase-3/7 Inhibitor II Ac-Asp-Asn-Leu-Asp-aldehyde (pseudo acid) is a peptide inhibitor of caspases. It blocks the activation of these proteases and their subsequent cleavage of substrates in the apoptotic pathway. This drug has potent inhibitory activity against caspases 3, 7, 8, 9, and 10. Caspase-3/7 Inhibitor II Ac-Asp-Asn-Leu-Asp-aldehyde (pseudo acid) specifically interacts with the active site and inhibits the enzyme by binding to an aspartic acid residue at position D197 in human caspase 3. Caspase 3/7 Inhibitor II Ac-Asp-Asn-Leu-Asp-aldehyde (pseudo acid) is localized to mitochondria and binds to acetyldeviceine (acDEV), a substrate for caspases
Chemical properties
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