Chlorphenesin

CAS: 104-29-0

Ref. 3D-FC11717

Product Information

• Name: Chlorphenesin
• Synonyms: 3-(4-Chlorophenoxy)-1,2-propanediol
• Brand: Biosynth
• Description: Chlorphenesin is a preservative that is used as an analytical agent in vivo to determine chemical stability and to maintain the pH of a solution. It has been shown to be stable in human serum at a concentration of 0.1% (w/v). Chlorphenesin is also a carbamate, which reacts with acidic compounds, such as benzalkonium chloride, to form chlorhexidine. In vitro assays have shown that chlorphenesin inhibits the enzyme acetylcholinesterase, which breaks down acetylcholine. This effect may be due to its ability to bind with serine hydroxyl groups on the protein. Chlorphenesin also has been shown to inhibit the activity of isoxsuprine hydrochloride, an inhibitor of cyclooxygenase-2 (COX-2), through competitive inhibition.

Chemical properties

• Molecular weight: 202.63 g/mol
• Formula: C₉H₁₁ClO₃
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C9H11ClO3/c10-7-1-3-9(4-2-7)13-6-8(12)5-11/h1-4,8,11-12H,5-6H2
• InChI key: InChIKey=MXOAEAUPQDYUQM-UHFFFAOYSA-N
• SMILES: OCC(O)COc1ccc(Cl)cc1