Product Information
- (m-Chlorophenyl)thiourea
- 1-(3-Chlorophenyl)Thiourea
- 1-(m-Chlorophenyl)thiourea
- 3-(Chlorophenyl)thiourea
- Brn 2090370
- N-(3-Chlorophenyl)thiourea
- Nsc 164965
- Thiourea, (3-chlorophenyl)-
- Thiourea, (3-chlorophenyl)- (9CI)
- Thiourea, N-(3-chlorophenyl)-
- See more synonyms
- Urea, 1-(m-chlorophenyl)-2-thio-
- m-Chlorophenylthiourea
1-(3-Chlorophenyl) thiourea is a curcumin analog that has been shown to inhibit the epidermal growth factor (EGF) receptor. It is synthesized from 1,2-dichlorobenzene and urea in a two-step process. The anhydrous potassium carbonate is first converted to the potassium salt with an acid chloride. The second step is the reaction of this salt with urea in the presence of excess anhydrous potassium carbonate. This product has been shown to be effective against cancer cells and may be used as a potential anticancer agent for treatment of skin cancer. 1-(3-Chlorophenyl) thiourea inhibits EGF receptor by binding to it and preventing its activation, which prevents cell proliferation and reduces tumor size.
Chemical properties
Technical inquiry about: 3D-FC12603 1-(3-Chlorophenyl) thiourea
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