N-(4-Chlorophenyl)glycine

CAS: 5465-90-7

Ref. 3D-FC130605

Product Information

• Name: N-(4-Chlorophenyl)glycine
• Synonyms: glycine, N-(4-chlorophenyl)-, Glycine, N-(4-chlorophenyl)-, Glycine, N-(p-chlorophenyl)-, (p-Chloroanilino)acetic acid, 2-(4-Chloroanilino)acetic acid, 4-Chloroanilinoacetic acid, Nsc 25860

Description

N-(4-Chlorophenyl)glycine is an antimalarial drug that has been shown to have significant antimalarial activity in a number of human cell lines. It is believed to work by blocking the electron transport chain, which leads to the production of reactive oxygen species and the disruption of mitochondrial membrane potential. The drug has an activation energy (Ea) of 92 kcal/mol and a reaction solvation energy (S0) of -14.7 kcal/mol. N-(4-Chlorophenyl)glycine also reacts with hydroxide solution and chloride to produce inorganic acid as a byproduct. This product is used for treating malaria caused by Plasmodium falciparum, Plasmodium vivax, and Plasmodium ovale.

• Brand: Biosynth

Chemical properties

• Molecular weight: 185.61 g/mol
• Formula: C₈H₈ClNO₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H8ClNO2/c9-6-1-3-7(4-2-6)10-5-8(11)12/h1-4,10H,5H2,(H,11,12)
• InChI key: InChIKey=FWALJUXKWWBNEO-UHFFFAOYSA-N
• SMILES: O=C(O)CNc1ccc(Cl)cc1