2-Chloro-5-methyl-1,3-benzoxazole

CAS: 3770-60-3

Ref. 3D-FC133875

Product Information

• Name: 2-Chloro-5-methyl-1,3-benzoxazole
• Synonyms: benzoxazole, 2-chloro-5-methyl-
• Brand: Biosynth
• Description: 2-Chloro-5-methyl-1,3-benzoxazole (CMB) is a regioselective synthetic intermediate that can be used to synthesize other compounds. It is produced by the reaction of chloromethyl methyl ether with anhydrous magnesium chloride in the presence of a solvent such as THF or diethyl ether. CMB can also be prepared by the reaction of 2,4,6-trichlorobenzoyl chloride with magnesium metal and a solvent such as THF or diethyl ether. This intermediate can be used in cross-coupling reactions with Grignard reagents to produce different compounds.

Chemical properties

• Molecular weight: 167.59 g/mol
• Formula: C₈H₆ClNO
• Purity: Min. 95 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C8H6ClNO/c1-5-2-3-7-6(4-5)10-8(9)11-7/h2-4H,1H3
• InChI key: InChIKey=AVJUFHRBOJNDFG-UHFFFAOYSA-N
• SMILES: Cc1ccc2oc(Cl)nc2c1