CH-223191
CAS: 301326-22-7
Ref. 3D-FC137662
| 1g | 1,885.00 € | ||
| 5mg | 234.00 € | ||
| 10mg | 395.00 € | ||
| 25mg | 716.00 € | ||
| 50mg | 1,085.00 € |
Product Information
- 1-Methyl-N-[2-methyl-4-[(2-methylphenyl)azo]phenyl]-1H-pyrazole-5-carboxamide
CH-223191 is a potent and selective DNA polymerase chain reaction (PCR) antagonist that prevents the synthesis of double-stranded DNA. It binds to the aryl hydrocarbon receptor (AHR), which is involved in mediating toxic effects of certain environmental pollutants. CH-223191 has been shown to be an AHR antagonist, preventing activation of proinflammatory cytokines such as IL-6 and IL-8 in human hepg2 cells. This agent also inhibits the expression of proinflammatory genes, including MMP-9, COX-2, and TNF-α. Additional studies have shown that CH-223191 has lead optimization potential for anticancer drugs due to its ability to inhibit proliferation and induce apoptosis in cancer cells at low levels.
Chemical properties
Technical inquiry about: 3D-FC137662 CH-223191
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