Finafloxacin

CAS: 209342-40-5

Ref. 3D-FC138682

Product Information

• Name: Finafloxacin
• Synonyms: 8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic aci d, 3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-, 8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, Bay-35-3377, By-377, Finafloxacin Hydrochloride, Xtoro

Description

Finafloxacin is a natural compound that belongs to the class of oral cephalosporins. It has shown activity against a wide range of bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, and Staphylococcus aureus. Finafloxacin is active against a variety of infectious diseases such as urinary tract infections caused by Escherichia coli and Proteus mirabilis and respiratory tract infections caused by Streptococcus pneumoniae. The drug has been shown to inhibit bacterial growth by binding reversibly to the enzyme dihydropteroate synthase (DHPS) that is required for folate synthesis. This inhibition prevents the production of tetrahydrofolate, an essential cofactor for the synthesis of thymidylate and other important biomolecules. Finafloxacin has also been shown to be effective in vivo in animal models with pharmacokinetic properties similar

• Brand: Biosynth

Chemical properties

• Molecular weight: 398.39 g/mol
• Formula: C₂₀H₁₉FN₄O₄
• Purity: Min. 95%
• InChI: InChI=1S/H3N/h1H3
• InChI key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1c(N2C[C@@H]3NCCO[C@H]3C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12